SSF-morph is an online tool designed to streamline the formatting and validation process for GWAS summary statistics files, specifically tailored for submission to the GWAS Catalog.
1.1 Please grant the permission to read and edit files in one of your local directories
1.2 Please select your input file
2.1 Please specify the delimiter in the input file: ; and please specify the first character in the line which indicates that this line is a comment: . (Note: please leave any fields empty if they are not applicable.)
2.2 Please select the appropriate analysis software from the dropdown menu:
Preview how your configuration changes the input file using the `Test` button, and then edit the configuration
Configuration:
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Your output:
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It's time to apply your configuration to your input file. The formatted result will then be downloaded to the folder you have permitted.
5.1 If you have not granted permission to read and edit files from your local directory in STEP 1, please click the . Otherwise, you can skip this step and select the file you want to validate
5.2 In your file, encountering fewer than 100,000 variants (rows) or zero p_values can lead to validation failure. To bypass the minimum row number requirement, and enable you to validate the rest of the file, please set the specific data validation requirements: the minimum number of rows should be and if you have zero-pvalues
For submission to the GWAS Catalog, lower row numbers may be permissible under certain circumstances (please contact gwas-subs@ebi.ac.uk to request an eligibility review). For files containing zero pvalues, analysis software type must be provided in the metadata template (see GWAS Catalog submission documentation for more details)
5.3 Click to validate the selected file