GWAS Catalog Blog

Latest News about the GWAS Catalog Project and web services

Streamlining GWAS Summary Statistics Data Interpretation with Improved YAML Metadata Feburary 22, 2024 By Yue Ji and Laura Harris

Having clear and accessible metadata is essential for enhancing data interpretation and ensuring its reusability. In the case of Genome-Wide Association Studies (GWAS), having a standardized and easy-to-understand format for documenting study metadata is crucial. In the GWAS Catalog, metadata associated with full genome-wide summary statistics files is accessible via multiple routes - searchable in the main Catalog via the website and REST API, ...

Ten years of the GWAS Catalog – Past, present and future Jun 28, 2018 By Laura Harris (GWAS Catalog) and Astrid Gall (Ensembl Outreach)

This year marks a special anniversary for the GWAS Catalog, as we have reached ten years since our launch in 2008. The GWAS Catalog is a widely used publicly available resource of all published human genome wide association studies (GWAS) and association results. Each GWAS study contains a wealth of information which is effectively inaccessible to researchers ...

Sharing is caring, why we need more freely available cancer GWAS summary statistics March 11, 2021 By Annalisa Buniello

The NHGRI-EBI GWAS Catalog is a central resource for the Genome Wide Association Study (GWAS) community, demonstrating the benefit of expert data curation and integration of full p-value GWAS summary statistics into a central repository for variant-trait associations. For more than 10 years, the Catalog has aimed to make GWAS data FAIR (Findable, Accessible, Interoperable and Re-usable) ...

A new standard for GWAS summary statistics July 20, 2022 By Laura Harris

Today we are very pleased to share our manuscript describing a new standard format for GWAS summary statistics, GWAS-SSF. The work towards this goal began in 2017 when we began to host summary statistics in the GWAS Catalog. It rapidly became apparent that summary statistics were formatted in a whole host of different ways, with only a few features in common between them, and little has changed since, with a recent analysis of 327 summary statistics ...

GWAS Catalog web search - new release! 12 July 2023 By GWAS Catalog team

We are pleased to announce the release of a new version of the GWAS Catalog web search interface, which is now in production. Here is a guide to the main differences you will see. ...

GWAS Catalog web search updates - help us with testing 5 May 2023 By GWAS Catalog team

We are pleased to announce the release of a new version of the GWAS Catalog web search interface, which is available for testing at www.ebi.ac.uk/gwas/labs. Here is a guide to the main differences you will see. ...

New submissions standard - release date 22 March 2023 By GWAS Catalog team

Next month the GWAS Catalog is switching to a NEW summary statistics format. Find out more about what this means for submitters and consumers of summary statistics ...

Cohorts now available in the GWAS Catalog Nov 14, 2023 By GWAS Catalog team

We are pleased to announce our latest data release includes a new version of the Catalog studies downloads containing additional fields describing the discovery stage (genome-wide) cohorts used in each study (see below for more details), and clearer information on the availability of full genomewide summary statistics. ...

Everything you need to know about the new GWAS Catalog Jun 13, 2018 By Annalisa Buniello

Genetic evidence could double the rate of success in drug targets identification - so the scientific community predicts. With this in mind, it is crucial for Open Targets to be able to feed as many SNP-trait associations as possible into its pipeline for systematic target identification and validation. ...

Trait annotation in the GWAS Catalog August 3, 2021 By Elliot Sollis

Each study in the GWAS Catalog investigates the association between variants in the human genome and a particular trait or phenotypic characteristic. For each study, we annotate the trait in two ways, a reported trait that reflects the author’s description of the disease or phenotypic characteristic under investigation. This is a free text description and sometimes. ...